The University of Sheffield was originally formed by the merger of three local institutions: the Sheffield School of Medicine, Firth College, and the Sheffield Technical School. With a history dating back to as early as the 1810s, the Sheffield School of Medicine is the university's oldest predecessor institution, which is also the oldest higher education establishment in Sheffield. In 1795, the General Infirmary was opened, becoming the first hospital in the city. Because of the apprenticeship-type training, the medical education at that time was largely unstructured. Regarded as the father of Sheffield's medical education, surgeon apothecary Hall Overend began to train medical students in 1811. His school of anatomy and medicine was externally recognised in 1828, and he conducted and taught human dissection in an anatomy museum at his home in Church Street. Overend, however, was not officially registered as a lecturer with the Society of Apothecaries, a recognised body for medical education. Physicians and surgeons of the General Infirmary suggested that a school associated with the hospital would be highly eligible for recognition by the society. As a result, in 1828, a public meeting was called by physician Sir Arnold Knight, and supported by Overend, to establish a new medical school. The Sheffield Medical Institution was formally opened a year later in 1829 on Surrey Street, with the Latin motto Ars longa vita brevis (Art is long, life is short), which refers to the difficulty to acquire and practice the art of Medicine. Knight laid the foundation stone and delivered the opening lecture.
The University Extension Movement emerged in the 1870s with the aim of providing education in the city which lacked any tertiary institutions. During the period, the steel industry in Sheffield was prospering and the city's population was doubled to around 240,000 from the 1840s. In 1871, the university extension scheme arrived in Sheffield, and a group of lecturers from the universities of Oxford and Cambridge travelled to the city giving lectures and educating people about the benefits of tertiary education. Steel manufacturer and former mayor of Sheffield Mark Firth and clergyman Samuel Earnshaw therefore organised courses in English literature and political economy. The courses became popular so Firth decided to donate £20,000 and purchase a site in the city centre (now Leopold Street and West Street) in 1877 to build a new institution for the classes. Firth College was founded during Firth's late year in 1879 and developed out of the Extension Movement scheme to teach arts and pure science subjects. The college saved the medical school, which had an insecure early history, from collapse and took over the teaching of all background subjects to medical students. In 1888 the medical school was relocated, opposite Firth College, to a new building on Leopold Street.
Firth College also helped to fund the opening of the Sheffield Technical School in 1884 to teach applied science, the only major faculty the existing colleges did not cover. The Sheffield Technical School was created by collecting funds within Firth College because of local concern about the need for technical training, particularly steelmaking in Sheffield. Former mayor of Sheffield Sir Frederick Mappin started to fundraise for the school and £10,240 was raised. A grant was secured in 1883 to fund a professor of Metallurgy and Mechanical Engineering. Many of the steel-making firms in Sheffield contributed to funding the Technical School, and research from the school in turn helped develop new processes and products for the companies. The Technical School was originally founded as a new technical department in Firth College, and in 1886, the school moved to St George's Square (later renamed Charlotte Street and now Mappin Street) on the site of the old Grammar School. William Ripper was appointed as Head of Mechanical Engineering at Firth College from 1889, then Principal of Sheffield Technical School.
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